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疼痛甩尾

疼痛甩尾主要是用于测量大、小鼠尾巴部受红外热刺激的痛觉阈值。 实验时,当动物感觉疼痛,尾巴会轻敲台面,内置传感器会立刻检测到,停止计时和关闭光源,即仪器自动记录反应时间和光源强度。数据可通过U盘、USB数据线等导出。
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37360
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疼痛甩尾主要是用于测量大、小鼠尾巴部受红外热刺激的痛觉阈值。
 
实验时,当动物感觉疼痛,尾巴会轻敲台面,内置传感器会立刻检测到,停止计时和关闭光源,即仪器自动记录反应时间和光源强度。数据可通过U盘、USB数据线等导出。
 
该仪器中有一可调强度的红外光源,其红外光主要是通过一抛物面反射镜聚焦在实验动物的尾巴上。实验时,操作人员将实验动物置于仪器上,把动物的尾巴放在红外光源处,接受刺激。
 
该仪器也可以在小鼠上进行实验,有小鼠设备配件可供选择。
延迟时间和强度能够通过USB或者串行端口导出。USB和软件都包含在内。
未找到相应参数组,请于后台属性模板中添加
  • 仪器自动记录实验数据
  • 精度高,避免人为因素引起的误差
  • 包含U盘和软件
  • 可独立工作,也可连接电脑使用
  • 仪器工作台表面无突出和遮挡物件
  • 操作方便,实验重复性好
  •  J.W. Little et alia: “Spinal Mitochondrial-Derived Peroxynitrite Enhances Neuroimmune Activation During Morphine Hyperalgesia and Antinociceptive Tolerance” Pain 154 (7): 978-986, 2013
  • P.J. McLaughlin et alia: “Behavioral Effects of the Novel Potent Cannabinoid CB1 Agonist AM 4054” Pharmacology Biochemistry and Behavior 109: 16-22, 2013
  • T.A. Kosten et alia: “A Morphine Conjugate Vaccine Attenuates the Behavioral Effects of Morphine in Rats” Progr. in Neuro-Psychopharmacol. and Biol. Psychiatry 45: 223–229, 2013
  • T.C. Chen et alia: “Spontaneous inflammatory Pain Model From a Mouse Line With N-ethyl-N-nitrosourea Mutagenesis” J. Biomed. Science 19 (55): 2–15, 2012 
  • J. Walsh et alia: “Disruption of Thermal Nociceptive Behaviour in Mice Mutant for the Schizophrenia-Associated Genes NRG1, COMT and DISC1” Brain Res. 1348: 114-119, 2012 
  • K. Guillemyn et alia: “In vivo Antinociception of Potent mu Opioid Agonist Tetrapeptide Analogues and Comparison with a Compact Opioid Agonist-neurokin 1 Receptor Antagonist Chimera” Molecular Brain 5 (4): 2-11, 2012 
  • A.J. Morrison et alia: “Design, Synthesis, and Structure–Activity Relationships of indole-3-heterocycles as Agonists of the CB1 Receptor” Bioorganic & Medicinal Chemistry Letters 21: 506-509, 2011  
  • M. Spetea et alia: “In vitro and in vivo Pharmacological Profile of the 5-benzyl Analogue of 14-methoxymetopon, a Novel μ Opioid Analgesic with Reduced Propensity to Alter Motor Function” Eur. J. Pharmac. Sciences 41: 125-135, 2010 
  • C.A. Boehm et alia: “Midazolam Enhances the Analgesic Properties of Dexmedetomidine in the Rat” Vet. Anaesthesia and Analgesia 37 (6): 550-556, 2010  
  • M.A. Philips et alia: “Myg1-Deficient Mice Display Alterations in Stress-Induced Responses and Reduction of Sex-Dependent Behavioural Differences” Behav. Brain Res. 207: 182-195, 2010
  • C. Dawson et alia: “ Dexmedetomidine Enhances Analgesic Action of Nitrous Oxide” Anesthesiology 100 (4): 894−904, 2004
  • P. Tolu et alia: “ Effects of Long-Term Acetyl-L-carnitine Administation in Rats: I. Increased Dopamine Output in Mesocorticolimbic Areas and Protection Toward Acute Stress Exposure” Neuropsychopharmacol. 27 (3): 410-420, 2002
  • R. Nadeson et alia: “ Potentiation by Ketamine of Fentanyl Antinociception. I. An Experimental Study in Rats Showing that Ketamine Administered by Non-Spinal Routes Targets Spinal Cord Antinociceptive Systems” Br. J. Anaesthesia 88 (5): 685−691, 2002
  • L. Jasmin et alia: “ The NK1 Receptor mediates Both the Hyperalgesia and the Resistance to Morphine in Mice Lacking Noradrenaline” PNAS 99 (2): 1029−1034, 2002
  • G.L. Fraser et alia: “ Antihyperalgesic Effects of Opioid Agonists in a Rat Model of Chronic Inflammation” Br. J. Pharmacol. 129: 1668−1672, 2000
  • M. Xu et alia: “ Effects of Radolmidine, a Novel α2- Adrenergic Agonist Compared with Dexmedetomidine in Different Pain Models in the Rat” Anesthesiology 93 (2): 473−481, 2000
  • A. Köster et alia: “Targeted Disruption of the Orphanin Fq/Nociceptin Gene Increases Stress Susceptibility and Impairs Stress Adaptation In Mice” Neurobiology 96 (18): 10444-10449, 1999
  • I. Sora et alia: “Opiate Receptor Knockout Mice Define µ Receptor Roles in Endogenous Nociceptive Responses and Morphine-Induced Analgesia” Neurobiology 94: 1544-1549, 1997C.T. Dourish et alia: "The Selective CCK-B Receptor Antagonist L-365,260 Enhances Morphine Analgesia and Prevents Morphine Tolerance in the Rat" Europ. J. Pharmacol. 176: 35-44, 1990
  • P.W. Nance & J. Sawinok: "Substance P-Induced Long-Term Blockade of Spinal Adrenergic Analgesia: Reversal by Morphine and Naloxone" J. Pharmacol. Exp. Therap. Vol. 240, No. 3: 972-977, 1987
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暂未实现,敬请期待
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