产品详情介绍
总览
iWorx RS-CMAP4-SA 专为研究复合肌肉动作电位 (CMAP) 和神经传导速度而设计。该系统还可用于4通道肌电图 (EMG) 记录,或肌电图和心电图 (ECG) 组合记录。针对啮齿动物和其他小动物的数据记录进行了优化。
产品特征
复合肌肉动作电位 (CMAP) 是神经肌肉电生理研究中的重要指标,指在刺激一条运动神经后,在该神经支配的肌肉上记录到的多个肌纤维动作电位的总和。啮齿动物的 CMAP 研究广泛应用于临床前神经科学和神经肌肉研究,以评估运动神经、神经肌肉接头和肌肉的功能。肌萎缩侧索硬化症 (ALS)、脊髓性肌萎缩症 (SMA)、腓骨肌萎缩症或周围神经病变等啮齿动物疾病模型通常使用 CMAP 来追踪疾病的发生和进展。坐骨神经受挤压或横断后,CMAP 记录可以评估功能性神经恢复的程度和时间。
刺激电极用于刺激特定的神经组织,皮下针式电极放置在受神经支配的肌肉组织上,软件控制电刺激输出,生物电放大器实时记录肌电信号,专业的CMAP高级分析软件模块用于分析波形图。
计算内容包括:
最大值:所选动作电位的最大振幅电压
最小值:所选动作电位的最小振幅电压
起始潜伏期:从周期或刺激开始到波形图首次偏离基线的时间
峰值潜伏期:从周期或刺激开始到波形图到最高点的时间
峰值前最大导数:峰值前动作电位的最大导数
峰值前最小导数:峰值前动作电位的最小导数
峰值后最大导数:峰值后动作电位的最大导数
峰值后最小导数:峰值后动作电位的最小导数
波幅:正向波顶点到负向波谷底的电压差
上升时间:从峰值开始到最大值的时间
最小时间:从峰值开始到最小值的时间
峰值停止:峰值结束的时间
周期持续时间:从峰值开始到峰值停止的时间
配置包括:
iWorx RA5s生理记录仪
LabScribe数据采集分析软件
EMG分析模块
皮下针式信号采集电极
高压皮下刺激电极
低压皮下刺激电极
参考文献
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