OsteoMetrics has been part of the bone histomorphometry community since 1989, serving researchers from major research institutions, CROs and pharmaceutical companies. Our main product OsteoMeasure has been used in over 400 laboratories all over the world. It was designed specifically for bone histomorphometry, following standard ASBMR nomenclature.

 Professional and efficient bone tissue morphology measurement and analysis, quantitative analysis of commonly used static and dynamic parameters of bone remodeling. Automatically calculate over 340 bone parameters, explaining the causes and processes of bone tissue morphological changes from the cell biological perspective. Static parameters include: Bone Volume/Tissue Volume (BV/TV), Trabecular Thickness (Tb.Th), Trabecular Number (Tb.N), Trabecular Separation (Tb.Sp), Osteoblast Surface/Bone Surface (Ob.S/BS), Osteoid Surface/Bone Surface (OS/BS), Osteonal Osteoid Surface (On.OS/BS), Number Osteoblasts/Bone Perimeter (N.Ob/B.Pm), Number Osteoclasts/Bone Perimeter (N.Oc/B.Pm), Osteoclast Surface/Bone Surface (Oc.S/BS), osteoclast surface area The dynamic parameters include: Mineralization Apposition Rate (MAR), Mineralizing Surface/Bone Surface (MS/BS), Eroded Surface/Bone Surface (ES/BS), Bone Formation Rate/Bone Surface (BFR/BS), Mineralized Area (Md.Ar), Activation Frequency (Ac.f), Osteoclast Surface/Bone Surface (Oc.S/BS), Osteonal Mineralizing Perimeter (On.M.Pm), Periosteal Mineralizing Perimeter (Ps.M.Pm), etc.

Effective and Efficient Measuring Tools

• Graphical overlays on live digital imaging for fast and efficient semi-automatic measurement

• Publication quality images at all magnifications with 20 Mpixel digital camera

• Ergonomic QHD Pen Touch Monitor for fast, efficient manual tracing

• Support for measurement of TIFF images

• Support for scanned image datasets

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• Xiaoting Zhang, et al., “Augmenting osteoporotic bone regeneration through a hydrogel-based rejuvenating microenvironment”, Bioactive Materials, Volume 41, November 2024