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Cancer / Tissue Oxygen Partial Pressure

OxyLite™ Pro

Oxford Optronix
OxyLite™ Pro
● Oxygen (pO2) & temperature monitor
● In vivo & in vitro applications
● Fully ‘plug and play’; no calibration procedures
● 2 or 4-channel monitors
● Enhanced productivity & features

Description

Overview

The survival of tissues and organs relies on an adequate supply of oxygen. The measurement of tissue oxygen tension (ptiO2) provides a direct measurement of the balance between oxygen supply (by the blood) and metabolic oxygen consumption (by the tissue), i.e. a readout of oxygen availability at the cellular level. This is in contrasts to spectroscopy (NIRS) techniques, which merely describe haemoglobin oxygenation status. 

Our OxyLite™ oxygen monitors will be of interest therefore to life scientists wishing to directly and continuously measure dissolved oxygen in the normal physiological as well as hypoxic ranges, both in experimental in vivo models, or in any number of in vitro applications.

Since 1998, when Oxford Optronix pioneered the commercialization of fibre-optic oxygen micro-sensor technology, the OxyLite™ brand has become established the world over in biomedical, boasting in excess of 500 peer-reviewed journal citations and hundreds of units sold worldwide.

2013 saw the culmination of a decade and half of continuous R&D with the launch of our third-generation of tissue oxygen monitors. Blending contemporary design, true plug and play convenience and the very latest in opto-electronic technology, our OxyLite™ Pro systems provide what is simply the most advanced, accurate and reliable tissue oxygen monitoring platform on the market.

Our oxygen sensors leverage state-of-the-art optical fluorescence technology intended for the quantitative measurement of oxygen partial pressure (pO2) and temperature in tissues, physiological fluids, cell cultures and other in vitro applications.  This technology offers key advantages over devices based on polarographic technology, making our oxygen monitors much easier to use and ideally suited to oxygen measurements in the typical physiological range, as well as incredibly sensitive under conditions of hypoxia.

Applications for OxyLite and OxyLite Pro include:

Tumour angiogenesis and oxygenation

Vital organ oxygenation during transplantation and shock monitoring

Cerebral oxygen during stroke

Brain and spinal cord injury

Tissue flap and wound oxygenation

pO2 monitoring in the eye

Dissolved oxygen measurement in hypoxic cell culture, bioreactors etc.

Statement of intended use:

OxyLite™ and OxyLite™ Pro are intended for laboratory, industrial and research use only.

OxyLite™ and OxyLite™ Pro are NOT intended for use in human subjects/patients.

Features

  • The easiest-to-use dissolved oxygen monitors in the world!

  • Absolute units of dissolved oxygen

  • Sensitivity and accuracy

  • No oxygen consumption

  • Microchip sensors

  • Touch-screen display and interface

  • Built-in temperature compensation

  • Versatility

  • Minimally invasive for in vivo applications

  • MRI compatibility

  • Multi-channel productivity

  • Upgradeable

  • Single-sensor multi-parameter monitoring

  • USB digital output

  • Analogue outputs

Journal Citations