Description
Overview
The RS-CMAP-SA is built specifically to study Compound Muscle Action Potential (CMAP) and Nerve Conduction Velocity. This system can also be used for 4-8 channels of EMG recordings, or a combination of EMG and ECG recordings. It is optimized for recording data from rodents and other small animals.
Features
The Compound Muscle Action Potential (CMAP) refers to the collective electrical response of a muscle following stimulation of its motor nerve. CMAP studies in rodents are widely used in preclinical neuroscience and neuromuscular research to evaluate the function of motor nerves, neuromuscular junctions, and muscle. Rodent models of diseases like Amyotrophic Lateral Sclerosis (ALS), Spinal Muscular Atrophy (SMA), Charcot-Marie-Tooth disease, or Peripheral Neuropathy often use CMAPs to track disease onset and progression. After sciatic nerve crush or transection, CMAP recordings can assess the degree and timing of functional nerve recovery
CMAP Advanced Module
Use a Stimulus Channel to mark the beginning of the stimulus
Mark the start and stop of the peak based on slope change, or the point where the line of maximum derivative intersects the baseline
Measure the Latency to the start of the peak as well as to the Max.
Calculations include:
Maximum: Maximum amplitude voltage for the selected action potential.
Minimum: Minimum amplitude voltage for the selected action potential.
Latency Start : Time from start of the cycle or Stimulus to the Peak Start
Latency Peak : Time from start of the cycle or Stimulus to the Peak Maximum
Pre Max dAdt: Maximum derivative of action potential before the peak.
Pre Min dAdt: Minimum derivative of action potential before the peak.
Post Max dAdt: Maximum derivative of action potential after the peak.
Post Min dAdt: Minimum derivative of action potential after the peak.
Amplitude: Plto – PeakStartAmplitude.
Rise Time: Time from PeakStart to Maximum.
Minimum Time: Time from PeakStart to Minimum.
Peak Stop: Time where the peak ends.
Cycle Duration: Time from PeakStart to PeakStop
System Includes:
IX-RA-5S Data Acquisition System
LabScribe Data Acquisition and Analysis software
LabScribe EMG Analysis Module
Platinum Needle Electrodes
C-BNC-PN2 stimulator Electrodes
C-HVS-PN2 high voltage Electrodes
Journal Citations
- Crouch, Michael S., Mingde Zheng, and Michael S. Eggleston. “Natural Typing Recognition vis Surface Electromyography.” arXiv preprint arXiv:2109.10743 (2021).
- Djabakatie, Zakiyat. “Function of spiny dorsal fin erector muscles in the bluegill, Lepomis macrochirus.” (2021).
- Yen, Patrick Szu-Ying, et al. “Upregulation of Glutamatergic Receptors in Hippocampus and Locomotor Hyperactivity in Aged Spontaneous Hypertensive Rat.” Cellular and Molecular Neurobiology (2021): 1-13.
- Bao, Xinqi, Aimé Kingwengwe Abdala, and Ernest Nlandu Kamavuako. “Estimation of the Respiratory Rate from Localised ECG at Different Auscultation Sites.” Sensors 21.1 (2021): 78.
- Zhang, Yi, et al. “Stretch-induced sarcoplasmic reticulum calcium leak is causatively associated with atrial fibrillation in pressure-overloaded hearts.” Cardiovascular research 117.4 (2021): 1091-1102.
- Ibsen, Lasse W., and Samuel Schmidt. “Seismocardiography as method for studying acute alcohol related hemodynamic changes.“(2020).
- Quint, Clay. “Tissue‐engineered vessel derived from human fibroblasts with an electrospun scaffold.” Journal of Tissue Engineering and Regenerative Medicine (2020).
- Bao, Xinqi, et al. “Comparison between Embroidered and Gel Electrodes on ECG-Derived Respiration Rate.” 2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). IEEE, 2020.
- Lee, Jiho, et al. “An Efficient Noninvasive Neuromodulation Modality for Overactive Bladder Using Time Interfering Current Method.” IEEE Transactions on Biomedical Engineering (2020).
- Hodge, Jacob, and Clay Quint. “Tissue engineered vessel from a biodegradable electrospun scaffold stimulated with mechanical stretch.” Biomedical Materials (2020).
- Lee, Hsiang-Chun, et al. “The sodium–glucose co-transporter 2 inhibitor empagliflozin attenuates cardiac fibrosis and improves ventricular hemodynamics in hypertensive heart failure rats.” Cardiovascular diabetology 18.1 (2019): 45.
- Azad, Md Khurshidul, et al. “Monitoring Intracranial Pressure Using Non-Invasive Brain Stethoscope.” SoutheastCon 2018. IEEE, 2018.
- Craighead, Daniel H., et al. “Ingestion of transient receptor potential channel agonists attenuates exercise‐induced muscle cramps.” Muscle & nerve 56.3 (2017): 379-385.
- Shiou, Yi-Lin, et al. “High fat diet aggravates atrial and ventricular remodeling of hypertensive heart disease in aging rats.” Journal of the Formosan Medical Association (2017).
- Munck, Kim, et al. “Body surface mapping of the mechanical cardiac activity.” Computing in Cardiology Conference (CinC), 2016. IEEE, 2016.
- Struijk, Johannes J., et al. “Heart-valve sounds obtained with a Laser Doppler Vibrometer.” Computing in Cardiology Conference (CinC), 2016. IEEE, 2016.